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Tree Allergies
Genetics can explain if you are allergic to pollen or certain foods?
Tree Allergies
Models of white blood cells and determine how genetically determined HLA DQ and DR genes have been identified with an increased risk of allergy to pollen, dust, latex and food. The fascinating aspect of this story is that there is an advantage of know your type of HLA DR and DQ in the evaluation of the risk of allergies to pollen and food allergies or tailsreactions.
Tree Allergies
Genetics of Food Reactions and Allergies
Tree Allergies
As I explain in more detail in my articles on the genetics of gluten sensitivity, we all have proteins on the surface of our cells that are genetically determined. These patterns are easily detectable by testing cells from blood or from the mouth obtained by a Q-tip type swab. Specific patterns have been associated with increased risk for autoimmune conditions, gluten sensitivity and celiac Disease.
HLA DQ gene and celiac disease or gluten intolerance
HLA DQ2 is present in over 90% of people who have celiac disease, while in most other HLADQ8, but not all people with celiac disease were found DQ2 and / or DQ8.
DQ and DR genetic patterns of food allergies and sensitivities to pollen or online?
Now it seems some models of DQ and DR are associated with pollen and food>allergies as well. As the Food Doc, I continue to search the literature for more information about genetic links to food allergy and intolerance. My search has led to me to a couple of interesting articles in the unusual area of oral allergy syndrome (OAS). The relationship between seasonal and perennial nasal allergies and food allergies is certainly well established but not generally known by most doctors or patients. It appears that some of us need to avoid eating certain foods if we have hay fever or allergies, especially during the hay fever season. This problem also appears to be inherited.
Research Documents Genetic Association With Certain Food and Pollen Allergies
Boehncke, et al. from the University of Frankfurt reported in 1998 that certain white blood cell types known HLA class II genotypes or HLA DQ and DR genetic patterns were found more frequently in people with certain pollen associated food allergies. HLA-DQB1*0301 is present in more people with grass pollen allergy. Those with HLA-DRB1*08, an inherited white blood cell protein pattern linked with a grass pollen allergy, have six times the increased risk of peanut allergy. Those who have inherited the HLA-DRB1*12 white blood cell pattern are 13 times higher at risk for carrot allergy.
Tree Pollen Allergy to Birch Tree Pollen Appears to be Pires
Allergy to birch pollen, hazelnut associated HLA-DRB1 * 01, DQA1 * 0101 and DQB1 * 0501 is associated. Hazelnuts, almonds, walnuts and the apple of most common food allergies associated with birch pollen. Allergies to these foods often associated with birch pollen in other studies.
Weed allergies and food intolerance associated
In 2004, Wang et al. published in China, the legacyType of white blood DQA1 * 0302 is more people with Artemisia pollen allergic rhinitis, hay fever are found in grass or mugwort wormwood. Ragweed allergy with multiple food allergies, including Apple, celery, hazelnut, pistachio, salad, almonds , associated with peanuts and carrots.
Where to find the genetic testing
There are three commercial laboratories that I am aware that giving full DQ'm HLA typing. These are laboratories of Quest, the laboratoryBonfils in Denver, and Enterolab. Bonfils is Enterolab genetic testing. Enterolab offers tests on samples of cells from a Q-tip Q-tip to run into his mouth. The test can be obtained directly from Enterolab without a prescription from a doctor if you are not covered by insurance. However, it is very reasonable from the point of genetic testing for $ 149. Bonfils non-DQ typing of cells derived from blood samples sent to other laboratories.
The future of genetic testingAllergies to pollen and food
In the future, these tests should be useful for evaluating suspected allergies, intolerances and allergies from pollen. In the meantime, those of us interested in this story interesting to look forward to further research in this exciting field. Dr. Fine, the founder of the reasons was associated with HLA DQ Enterolab published microscopic colitis. He found that microscopic changes in the colon or large intestineare similar if not identical to what you see in the small intestine in celiac disease. Several articles of the document now working on a gluten-free diet for many people with microscopic colitis, lymphocytic and collagen. It also helps a lot to Crohn's disease and ulcerative colitis.
The finding of intraepithelial lymphocytosis in the distal small intestine (ileum) is associated with an increased incidence of celiac disease in the proximal small intestine. Now, in addition to the plot,Link to this article has inherited some reason, the gene for white blood test for allergies to pollen and food allergy cross-reactions, which are generally accepted, but rarely followed up clinically. Oral allergy syndrome (OAS), also called the "syndrome of burns mouth, "occurs in many people, but the symptoms are often not diagnosed. include burning, pain and / or itching of the mouth or throat, with or without edema, which occurs almost immediately after consumption of certainDiet. Foods that are too often these reactions with pollen, dust, or latex allergies.
Unusual combination of burning mouth and pollen allergies or reactions to food
This unusual combination of trees, grass and grass pollen, dust mites and latex allergy reactions to foods, but there are also documented in the medical literature, often unrecognized by physicians or patients. The literature contains many reports OASfood allergies or intolerances to certain pollens, dust, mold, or allergic to latex. One of the best examples is the allergy to ragweed pollen. There is a high risk of allergy or food intolerance to certain foods. These foods are part of the family Cucurbitaceae (melons and cucumber) and banana. On the other hand, allergy to birch pollen is associated with a sensitivity to many foods. The list contains foods in the family Rosaceae (apples, pears), the family of nuts (hazelnuts, almonds, walnuts), potatoes and carrots. Reactions are classic allergic reactions like skin rashes (atopic dermatitis), urticaria, wheezing (asthma), runny nose (allergic rhinitis), and symptoms of burning in the mouth of the OAS and other symptoms of food intolerance.
If you have a food allergy, intolerance or sensitivity suspect Receive an expertise
People who suspect foodAllergy "or intolerance are advised to check the connection of pollen-food and a proper evaluation of food allergies, intolerances and sensitivities. The food contains gluten sensitivity and sensitivity to cow's milk (casein) the sensitivity of the protein. Food intolerance are the 'lactose intolerance. Food allergies are separate and distinct from both food sensitivities or intolerances.
Let us first consider genetic testing or ask your doctor to seeTheir
This new information on the relationship between the structure of proteins in the blood of white blood cells, HLA DQ type, suggests that we should consider genetic testing. After appropriate assessment,
Get a score of basic symptoms and diet food diary symptoms begin
I invite everyone to a score of basic symptoms for the development. A detailed food diary of symptoms before a process of elimination diet is also very useful. An elimination diet that excludes foods importantLectins (dairy products, cereals, legumes and nightshades) and list all the foods recommended by the pollen allergy which is, before accepting the diagnosis of IBS, fibromyalgia, neuropathy, or unexplained head pain and chronic fatigue. All the symptoms are not easy to explain or to be established with other improved diagnosis and treatment is considered as a cause of a reaction to food components, until proven otherwise.
Selected Bibliography
Boehncke, et al. Clin Exp Allergy.April 1998, 28 (4) :434-41.
Fine KD et al. Am J Gastroenterol. August 2000, 95 (8) :1974-82.
Wang et al. Otolaryngol Head Neck Surg February, 130 (2): 192-197.
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